Senior Research Scientist, Precision Oncology

Company: Aitia
Location: Somerville
Posted on: September 18, 2023

Job Description:

Company Overview Aitia is the leader in the development and application of Causal AI and Digital Twins to discover the next generation of breakthrough drugs in neurodegenerative disorders, oncology, and immunology. By leveraging the convergence of multi-omic patient data, high-performance computing, and causal learning and AI, Aitia is revealing the hidden biological mechanisms of disease to create Digital Twins. Gemini Digital Twins are being used today to discover novel therapies and accelerate R&D in Alzheimer---s Disease, Parkinson---s Disease, Huntington---s Disease, multiple myeloma, prostate cancer, and pancreatic cancer, with several more in development. Aitia---s partners include six of the top ten pharmaceutical companies, leading academic research and medical centers, medical societies, leading multi-omic data companies, and patient advocacy groups globally. Position Summary The Senior Research Scientist will join a dynamic Precision Oncology team to apply Aitia---s powerful Causal AI platform to oncology drug discovery and clinical development. The candidate will work closely with scientists at major biopharma and emerging drug discovery companies to deliver unique scientific insights for decision making. The candidate will be responsible to work with internal and external teams to formulate scientific questions into coherent analytical efforts for causal analysis and derive novel biological insights for disease mechanism and to develop prognostic and predictive biomarkers. The candidate will carry out these projects using Aitia---s proprietary Causal AI modeling and simulation platform and synthesize these results with relevant literature and bioinformatics resources. They will communicate scientific findings to partners and collaborators and contribute to presentations at scientific conferences and publications. Principal Duties and Responsibilities: Serve as the scientific project lead to collaborate with clients to frame research questions, propose solutions, and support analytical needs to ensure the best application of causal AI technology for novel therapeutic discovery and development Contribute to cross team efforts to build in silico patient causal AI models and research into novel model applications for oncology therapeutic discovery Contribute to novel cancer genomics knowledge generation through deep data mining from public/proprietary multimodal datasets. Communicate technical results clearly and concisely to collaborations, discuss how to incorporate information into their processes, and achieve high client satisfaction Manage and complete external facing projects of high complexity in a timeline driven manner Maintain expertise in state-of-the-art data science and cancer genomics methods Job qualifications: Advanced degree in quantitative science or life science with 3 years of working experience in the area of cancer genomics. Solid understanding of statistical analysis principles and expert user of the statistical data analysis tools, such as R/Bioconductor or Python. Experience working with multi-omics data, single cell data, and high-throughput screening data Familiarity with major cancer genomics / bioinformatics databases and tools Experience working with advanced ML techniques, probability theory, Bayesian analysis, or causal inference methods preferred Prior experiences working with hematology oncology, immuno-oncology, or drug discovery are desirable Must be a team player and willing to help and ask for help; excellent written and verbal communication skills; excellent interpersonal skills with a proven record of interacting with bench scientists effectively. Company Culture Our philosophy at Aitia is simple: we cannot transform drug discovery and development with anything less than an all-star team. We are seeking smart, driven people who are experts in their field, have a track record of success, and a passion for creating change. We believe that strong teams supercharge the performance of individuals, create a fun and dynamic workplace, and provide first-class results for our clients and the people they serve. We are passionate about our work and believe in the ability of our technology to change the world. Our core values of integrity, collaboration, value, diversity, and game-changing initiatives guide our behaviors with each other and our clients. Aitia offers competitive salaries, stock options, unlimited vacation, health, dental and vision insurance, life insurance, long-term disability, 401(k), parental leave, tuition reimbursement, professional development, subsidized parking/MBTA pass, tasty food, volunteering opportunities, social gatherings, and more. Equal Employment Opportunity Aitia provides equal employment opportunities to all employees and applicants for employment without regard to race, color, national origin, religion, sexual orientation, gender, gender identity or expression, age, veteran status, disability, pregnancy or conditions related to pregnancy, or genetics. In addition to federal law requirements, Aitia complies with applicable state and local laws governing nondiscrimination in employment in every location in which the company has facilities.

Keywords: Aitia, Somerville , Senior Research Scientist, Precision Oncology, Healthcare , Somerville, Massachusetts