Principal Scientist, Translational Bioinformatics
Company: Bristol Myers Squibb
Location: Somerville
Posted on: January 14, 2021
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Job Description:
At Bristol Myers Squibb, we are inspired by a single vision ---
transforming patients--- lives through science. In oncology,
hematology, immunology and cardiovascular disease --- and one of
the most diverse and promising pipelines in the industry --- each
of our passionate colleagues contribute to innovations that drive
meaningful change. We bring a human touch to every treatment we
pioneer. Join us and make a difference.We are seeking an innovative
scientist to join our NGS and Proteomics support team in the
Translational Bioinformatics group. This group of computational
scientists is responsible for advancing Bristol-Myers Squibb---s
industry-leading pipeline in multiple therapeutic areas (including
Immuno-Oncology, Cardiovascular, Fibrosis, and Immunoscience)
through the strategic application of cutting-edge bioinformatics
approaches. The scientists in this group analyze real-world health
data, design experiments and analyze both pre-clinical and clinical
-omics data sets, including RNA-Seq, Exome and Whole Genome
Sequencing, single-cell sequencing, high-throughput proteomics, and
multiplex flow cytometry in order to nominate novel drug targets,
enable patient enrichment strategies, and guide drug development
decisions. The group interacts with and influences all aspects of
R&D at BMS, from early discovery through late-stage
development.ResponsibilitiesEstablish best practices for various
RNASeq and DNA QC workflowsDevelop methodology to identify
biomarkers using machine learning and artificial
intelligenceCommunicate NGS QC best practices across all relevant
teamsQualifications:Ph.D. in Bioinformatics, Computational Biology
or another relevant field or M.Sc. in one of the same fields and 5
years of experience in the fieldExcellent working knowledge of
RNASeq and DNASeq workflowsExtensive hands on experience with
common NGS tools (samtools, picard, etc.)Experience with ggplot2
and other R graphing solutionsSome statistics background is
desirableFamiliar with methods used in machine learning (ML) and
artificial intelligence (AI) is required.Fluency with Linux-based
high-performance computing environments, AWS cloud computing,
R/Bioconductor, and reproducible research practicesStrong
problem-solving and collaboration skills, and rigorous and creative
thinkingExcellent written and oral communication skills, including
an ability to explain complex ideas to computational scientists,
experimentalists, and cliniciansAround the world, we are passionate
about making an impact on the lives of patients with serious
diseases. Empowered to apply our individual talents and diverse
perspectives in an inclusive culture, our shared values of passion,
innovation, urgency, accountability, inclusion and integrity bring
out the highest potential of each of our colleagues.Bristol Myers
Squibb recognizes the importance of balance and flexibility in our
work environment. We offer a wide variety of competitive benefits,
services and programs that provide our employees with the resources
to pursue their goals, both at work and in their personal
lives.Full time
Keywords: Bristol Myers Squibb, Somerville , Principal Scientist, Translational Bioinformatics, Other , Somerville, Massachusetts
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