Sr Engineer II, Gene Therapy Process Development - Purification

Company: Biogen Idec
Location: Somerville
Posted on: May 3, 2021

Job Description:

Job DescriptionAbout This RoleThis role will play a critical part in the development of a viral vector downstream platform process and its application to Biogen's gene therapy pipeline of products. You will independently design and conduct experiments for multiple aspects of purification development activities, including column and membrane chromatography (e.g., affinity, ion exchange), filtration and membrane separations (e.g., TFF, depth filtration), scale-up, and technology transfer to the manufacturing organizations. This role reports into the Director, Gene Therapy Process Development and will be expected to work independently, manage projects, manage a team of scientists/engineers and participate in cross-functional, multidisciplinary project teams.What You'll DoInvestigate and evaluate novel technologies to improve current purification processes used for the clinical and commercial manufacturing of adeno-associated viral (AAV) vectorsIndependently design and execute experiments (DOE) to generate optimum and robust purification processesInteract with other departments such as cell culture development, analytical development, and manufacturing sciencesWrite and review high quality technical development and technology transfer reportsParticipate in scientific conferences and make contributions to scientific publications and patentsWho You AreYou are passionate and innovative in how you drive gene therapy technology. You love building processes, platforms and dealing with difficult scientific challenges.#LI-CL1QualificationsRequired SkillsPh.D. in chemical engineering, biochemical engineering, biochemistry, or a related field with 2-5 years of relevant experience, Master's degree with 6-8 years of relevant experience or a Bachelor's degree with a minimum of 8 years of relevant experienceA strong understanding of viral vector properties and experience with development of downstream processes for viral vectorsAbility to generate, develop, and implement innovative ideas and deal with difficult scientific problems is essentialA strong understanding of the fundamentals of chromatography and/or membrane separationsHands-on experience with AKTA chromatography and filtration systemsStrong verbal and written communication skills are integral to this positionPreferred SkillsA working knowledge of Good Manufacturing ProceduresPrevious managerial experienceAdditional InformationOur mission to find therapies for neurological and rare diseases is a unique focus within our industry and this shared purpose is what connects us a team. We work together to overcome obstacles and to follow the science. We are resilient as we strive to make an impact on our patients' lives and on changing the course of medicine. Together, we pioneer. Together, we thrive.SummaryType:Full-timeFunction: ScienceSDL2017

Keywords: Biogen Idec, Somerville , Sr Engineer II, Gene Therapy Process Development - Purification, Other , Somerville, Massachusetts